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Forum -> Coronavirus Health Questions
If immunity doesn't last, how will a vaccine help?



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amother
OP


 

Post Tue, May 05 2020, 6:13 pm
I'm not understanding something here. When people used to get the measles, they were considered to have lifelong immunity (and that still remains true for those who were not immunized and had measles.) Then, we started to vaccinate people with 1 and then 2 doses of measles and they were considered to have long-term immunity to measles. Yes, it could wear off and a booster might be needed, but immunity is assumed in most cases at least for 10 years. If someone is unsure if they're still immune, they can take a blood test to check their antibody levels. If they show a specific antibody level, we say they're immune.

With corona virus, we are saying that unlike measles, someone who had corona virus, even with having antibodies in their blood, may still be at risk of getting it again.

How will a vaccine help? I don't understand. If antibodies are protective, then getting the virus should be protecting from having it again. If antibodies are not protective, then how will having antibodies from a vaccine help anything?
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amother
Lime


 

Post Tue, May 05 2020, 6:16 pm
We may need to take the vaccine annually like the flu.
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amother
Coffee


 

Post Tue, May 05 2020, 6:20 pm
some vaccines in the works are using different models, such as one I read about that will send messenger rna into the nuclei of our cells instructing it to make antibodies that disable the specific ace2 receptors that the virus uses to enter cells, immediately upon detection.
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Simple1




 
 
    
 

Post Tue, May 05 2020, 6:21 pm
amother [ Lime ] wrote:
We may need to take the vaccine annually like the flu.


Then immunity should still last for the season.
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amother
Scarlet


 

Post Tue, May 05 2020, 6:24 pm
amother [ Lime ] wrote:
We may need to take the vaccine annually like the flu.

...to get a 1% smaller chance of getting the flu.
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amother
Aquamarine


 

Post Tue, May 05 2020, 6:30 pm
nothing has been established yet so its all hearsay so far
Its safe to assume once you fought off the virus you are immune for some time, hopefully even for life
Right now the issue you are probably getting at... we dont know how long the virus stays alive in you even after you recovered. It seems there were many who tested positive weeks after recovery, and although previously reported that it's possible they have contracted the virus again, that doesn't seem to be the case. The virus was still there doing it's thing even after the person felt ok
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HonesttoGod




 
 
    
 

Post Tue, May 05 2020, 6:53 pm
They don’t know.
They don’t know if you have immunity. They don’t know if and how the covid19 can change.

They’re developing vaccines because like the flu, it protects the vulnerable. Without a flu shot thousands more would die each year. Whilst it’s not fool proof it does give a much milder version of the flu should
One get it. Which for the elderly and vulnerable is huge. And for many it protects us which as we’ve seen with covid19, the more of us protected the less it spreads like wildfire.
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amother
Red


 

Post Tue, May 05 2020, 6:58 pm
amother [ Coffee ] wrote:
some vaccines in the works are using different models, such as one I read about that will send messenger rna into the nuclei of our cells instructing it to make antibodies that disable the specific ace2 receptors that the virus uses to enter cells, immediately upon detection.
This is genetically modifying your own DNA. So scary.
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amother
Coffee


 

Post Tue, May 05 2020, 7:00 pm
amother [ Red ] wrote:
This is genetically modifying your own DNA. So scary.
I agree, it's scary. Just repeating what I read.
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amother
Apricot


 

Post Tue, May 05 2020, 7:03 pm
South Korea says recovered coronavirus patients who tested positive again did not relapse: Tests picked up 'dead virus fragments'

https://www.businessinsider.co.....020-4
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amother
Coffee


 

Post Tue, May 05 2020, 7:05 pm
amother [ Apricot ] wrote:
South Korea says recovered coronavirus patients who tested positive again did not relapse: Tests picked up 'dead virus fragments'

https://www.businessinsider.co.....020-4
This just means that the virus confers some sort of immunity. We still don't know for how long.
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Sunny Days




 
 
    
 

Post Tue, May 05 2020, 7:05 pm
from what I understand as a simple layman, the difference between lets say measles and something like the flu or probably covid as well, is that these viruses mutate- so immunity from the disease itself or a vaccine will be much more long lasting in a measles situation than a virus like covid. as the virus mutates and different strains circulate you may have less protection.
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amother
Coffee


 

Post Tue, May 05 2020, 7:09 pm
gamzehyaavor wrote:
from what I understand as a simple layman, the difference between lets say measles and something like the flu or probably covid as well, is that these viruses mutate- so immunity from the disease itself or a vaccine will be much more long lasting in a measles situation than a virus like covid. as the virus mutates and different strains circulate you may have less protection.
The length of time that a virus confers immunity isn't just about it mutating. Some very stable viruses don't give lifelong immunity. They are saying this coronavirus is fairly stable, but we still don't know how long the antibodies will last.
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amother
Apricot


 

Post Tue, May 05 2020, 7:09 pm
Based on SARS. Among 176 patients who had had severe acute respiratory syndrome (SARS), SARS-specific antibodies were maintained for an average of 2 years, and significant reduction of immunoglobulin G–positive percentage and titers occurred in the third year. Thus, SARS patients might be susceptible to reinfection >3 years after initial exposure.

So I would assume that there is immunity for at least a year or 2.

https://www.ncbi.nlm.nih.gov/p.....1497/
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amother
Pewter


 

Post Tue, May 05 2020, 7:13 pm
amother [ OP ] wrote:
I'm not understanding something here. When people used to get the measles, they were considered to have lifelong immunity (and that still remains true for those who were not immunized and had measles.) Then, we started to vaccinate people with 1 and then 2 doses of measles and they were considered to have long-term immunity to measles. Yes, it could wear off and a booster might be needed, but immunity is assumed in most cases at least for 10 years. If someone is unsure if they're still immune, they can take a blood test to check their antibody levels. If they show a specific antibody level, we say they're immune.

With corona virus, we are saying that unlike measles, someone who had corona virus, even with having antibodies in their blood, may still be at risk of getting it again.

How will a vaccine help? I don't understand. If antibodies are protective, then getting the virus should be protecting from having it again. If antibodies are not protective, then how will having antibodies from a vaccine help anything?


If there is absolutely no natural immunity, a vaccine won't work at all. If there is limited natural immunity, you will have to get a vaccine every X amount of years.

The whole immunity debate is ridiculous for 2 reasons. 1. If there is no, or very limited (2-3 months) worth of immunity, everything we're doing is stupid because no matter how much we SD, eventually we'll all just keep getting it and getting it until it kills us at which point this is the end of humanity anyway so we might as well just do nothing. And 2. If there is immunity and we decide to do some type of "immunity card" which allows people to resume activity if they have antibodies, people will intentionally infect themselves to get the immunity card which doesn't seem like a desirable outcome.
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amother
Magenta


 

Post Tue, May 05 2020, 7:25 pm
Noone knows...
IF there will be a vaccine
IF u are immune after having it
IF it will be over after we've all had it.
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mazeltov




 
 
    
 

Post Tue, May 05 2020, 7:27 pm
Maybe the vaccine can include a bunch of variations and mutations to protect from those?
... Which might also help build some immunity for future variations or mutations?
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Refine




 
 
    
 

Post Tue, May 05 2020, 7:32 pm
I have the sale question about all those who are donating blood plasma to the hospital.
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amother
Apricot


 

Post Tue, May 05 2020, 7:33 pm
Israel’s shadowy Biological Research Institute confirmed Tuesday that it has isolated an antibody it believes could be used to develop treatments against the COVID-19 virus, and said it was ahead of the world in its efforts, though it also warned that medication was still at least several months away.

This development would not be useful in the creation of a vaccine, but would rather be a move toward a drug treatment for those who have already contracted the disease. The antibody has also not yet been tested outside of a Petri dish.

https://www.timesofisrael.com/.....cure/
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amother
Coffee


 

Post Tue, May 05 2020, 7:35 pm
amother [ Apricot ] wrote:
Israel’s shadowy Biological Research Institute confirmed Tuesday that it has isolated an antibody it believes could be used to develop treatments against the COVID-19 virus, and said it was ahead of the world in its efforts, though it also warned that medication was still at least several months away.

This development would not be useful in the creation of a vaccine, but would rather be a move toward a drug treatment for those who have already contracted the disease. The antibody has also not yet been tested outside of a Petri dish.

https://www.timesofisrael.com/.....cure/
This is more of a drug/biologic. Nothing to do with immune memory.
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