According to study; Ivermectin causes male infertility

southernbubby

Wed, Sep 08 2021, 11:28 pm

WFLA

Ivermectin causes sterilization in 85 percent of men, study finds
Erin Coulehan
3 hours ago

WFLA Photo

EL PASO, Texas (KTSM) — The effects of Ivermectin therapy on human males can have an effect on men’s reproductive health.

Researchers at three universities in Nigeria studied the effects of Ivermectin, which is used to treat river blindness and other medical conditions in humans, on men’s sperm counts. According to their study, 85 percent of men who take Ivermectin become sterilized.

Ivermectin is often used as an anthelmintic to combat parasites in animals and some people have been using it to fight COVID-19 despite health experts’ recommendations against it.

The study conducted by researchers in Nigeria screened 385 patients with river blindness to investigate the effects of Ivermectin on sperm function.

The researchers found that 85 percent of all male patients treated in a particular center with ivermectin in the recent past who went to the laboratory for routine tests were discovered to have developed various forms, grades and degrees of sperm dysfunction.

Dysfunctions include the following:

Low sperm count
Poor sperm morphology
Two heads
Tiny heads
Double tails
Absence of tails
Albino sperm cells
Azoospermia, or the absence of motile sperm
Poor sperm motility
“There was a significant drop in the sperm counts of the patients after their treatment with Ivermectin,” the study’s authors concluded.
The United States Food and Drug Administration (FDA) has not authorized or approved Ivermectin for treating or preventing COVID-19 in humans or animals.

But across the country, people have been self-medicating using animal-grade Ivermectin.

“Never use medications intended for animals on yourself or other people. Animal Ivermectin products are very different from those approved for humans. Use of animal Ivermectin for the prevention or treatment of COVID-19 in humans is dangerous,” reports the FDA.

Dr. Ogechika Alozie, infectious disease expert in El Paso, said to use tried-and-true methods of COVID-19 treatment.

“The reality is this: the things that we know work so far, dexamethasone, actemra, remdesivir in the hospital. Things that work before you go to the hospital like antibody infusions and the vaccines have loads more data than Ivermectin,” he said.

Clinical trials evaluating whether Ivermectin tablets can be used to treat COVID-19 are ongoing, but there is currently no data available to suggest efficacy in fighting the virus.

Bottom line, vaccines are the best way to combat COVID-19.

“I get that people are scared, I get that people are worried,” said Alozie. “But it puzzles me that people would use something with such little data compared to something that has such great data and we know works.”

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Reality

Wed, Sep 08 2021, 11:47 pm

I don't doubt this study but honestly there have been so many studies it makes ones head spin!

I remember reading a study coming out of Israel that men recovering from covid had super low sperm counts and they were planning on tracking those men over a 5 year period.

Rappel

Wed, Sep 08 2021, 11:50 pm

But COVID in general can have a dreadful affect on men's fertility. What is River blindness? Does it function along similar pathways? I need to read the study before I can consider it rigorous enough to blame the medicine and not the disease

Though I agree that self-medicating with animal-approved medicines is not the route to go XD

Last edited by Rappel on Thu, Sep 09 2021, 6:20 am; edited 1 time in total

amother

Foxglove

Wed, Sep 08 2021, 11:51 pm

Sounds like survival of the fittest in action!

amother

PlumPink

Thu, Sep 09 2021, 12:02 am

How soon after infection were they tested? How did they isolate and compare the effects of covid and Ivermectin? Did they recheck 6 months? A year? Or maybe more later to see if it recovered on its own?

Too much is open here on a relatively small sample size.

I'm not advising ppl to take animal medication but this is really not adequate at all.

amother

cornflower

Thu, Sep 09 2021, 12:05 am

Link please?

amother

Peru

Thu, Sep 09 2021, 12:09 am

Not possible. Only the vaccine causes problems.
All sorts of off label and experimental drugs are fine as long as you don’t take the vaccine.

(Tongue in cheek for anyone who can’t tell)

amother

Tanzanite

Thu, Sep 09 2021, 12:11 am

Hmm
It's been used for many years by people.
Now they are trying to say that it doesnt treat covid but having a hard time with that...
So now all of the sudden it causes male infertility?
So interesting

amother

Diamond

Thu, Sep 09 2021, 12:48 am

Why would they do a study of a horse medication on humans?

WhatFor

Thu, Sep 09 2021, 1:22 am

amother [ cornflower ] wrote:

Link please?

I googled it and found this: https://www.wfla.com/community.....inds/

There's a link to the study in the article. Looks like it was published in 2011.

ETA: looks like it wasn't published in a very credible publication and this study is unverified
https://www.snopes.com/fact-ch.....-men/

Last edited by WhatFor on Thu, Sep 09 2021, 8:24 am; edited 1 time in total

sushilover

Thu, Sep 09 2021, 2:00 am

Thanks for sharing.

I'm a bit skeptical after the article about people ODing on Ivermectin in Oklahoma turned out to be completely made up. It's so sad that we can't trust the media these days when we need them the most.

southernbubby

Thu, Sep 09 2021, 6:07 am

sushilover wrote:

We have all seen a few good whoppers in both sides of the media. Nobody has a monopoly on the truth. There have been a slight increase in calls to poison control regarding ivermectin, particularly the veterinary formula but the hospitals are not full of people who took it. The hospitals are not claiming to be full of vaccine injuries either but if those take the form of heart attacks and strokes, are hospitals admitting an increase in those, and were the patients vaccinated?

southernbubby

Thu, Sep 09 2021, 6:10 am

amother [ Diamond ] wrote:

Why would they do a study of a horse medication on humans?

Ivermectin is no longer the drug of choice for river blindness:

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First new treatment for river blindness approved by U.S. FDA in 20 years
TDR news item
14 June 2018

The United States Food and Drug Administration (FDA) has approved moxidectin as the first new treatment for river blindness in 20 years, adding new ammunition to the fight to eliminate this disabling disease. The FDA decision followed priority review of a new drug application for a neglected tropical disease submitted by the not-for-profit biopharmaceutical company Medicines Development for Global Health (MDGH).

Physical examination of a study participant with onchocercal skin disease
Physical examination of a study participant with onchocercal skin disease
WHO/TDR
River blindness (onchocerciasis) is caused by the parasitic worm Onchocerca volvulus and transmitted to humans through exposure to repeated bites of infected black flies. Around 200 million people are at risk for the disease that causes severe itching, disfiguring skin conditions and visual impairment, including blindness. More than 99% of infected people live in 31 African countries.

Ivermectin, the only drug currently in use, distributed annually to entire communities living in endemic areas, has significantly reduced river blindness, but the global campaign to eliminate the disease requires also more effective drugs. Recently published findings of a large phase 3 clinical study managed by TDR and conducted in the Democratic Republic of Congo, Ghana and Liberia showed that moxidectin is superior to ivermectin in suppressing the presence of parasites (microfilariae) in the skin that cause the disease and are taken up by blackflies.

“We are delighted about the FDA’s decision,” says TDR Director John Reeder. “It is a milestone toward our vision to have moxidectin made available to African countries to quicken the river blindness endgame.”

Model use of tropical disease priority review voucher (PRV) by not-for-profit
This approval is a step forward for disease elimination strategies as well as innovative financing for more treatments of neglected tropical diseases.

Priority review by the FDA speeds up the new drug application process to six months (compared to the standard 10 months) and approval gives the applicant a transferable voucher (the PRV) that can be used or sold for priority review of another drug.

“This voucher to MDGH fully meets the original spirit of the PRV programme to promote research and development of affordable and accessible drugs for neglected tropical diseases. Without this programme, MDGH would not have been able to raise the funds to complete all of work for the new drug application,” says Dr Reeder.

TDR’s long-term commitment
TDR was instrumental in the evaluation of moxidectin for river blindness over nearly two decades of research and collaboration with academic groups, industry, investigators and river blindness control specialists, WHO country offices and other partners in disease-endemic countries.

WHO/TDR
“We acknowledge the extraordinary persistence and dedication of the team at TDR, without whom this drug approval would not have happened,” says Mark Sullivan, Founder and Managing Director of MDGH.

TDR began its commitment to river blindness control around 40 years ago, acting as the research arm of the Onchocerciasis Control Programme in West Africa (OCP), and then the African Programme for Onchocerciasis Control (APOC), also hosted by WHO.

This was part of TDR’s long-term commitment to find innovative solutions to developing new drugs for neglected conditions – including the repurposing of drugs from veterinary medicine, the pioneering of public-private product development partnerships, and researching effective strategies to implement public health programmes.

Following withdrawal of its industry partner in 2011, TDR managed completion of the phase 3 clinical trial alone, and searched for a new sponsor to register moxidectin for use in onchocerciasis and ensure its manufacturing, availability and affordability. In 2014 all data at TDR's disposal were licensed to MDGH, which raised funds from the Global Health Investment Fund (GHIF) to complete the work needed to meet the requirements for a new drug application to the FDA.

Next steps toward drug availability in endemic countries
MDGH has been preparing for the next steps toward drug availability in countries for months: “The FDA registration is a real achievement but we still have a number of steps to go until African countries can use moxidectin to accelerate elimination of this disabling disease – and we are counting on TDR and the river blindness research and control communities to work with us, says Mr Sullivan.”

“Our work to bring this medicine to those who need it most continues in earnest,” concluded Mr Sullivan. “The funds from the PRV sale will kick start the next set of activities to provide the community with additional data, including data in younger children.”

“We are here for the full journey – we have committed our skills and resources to play our part in ridding the world of this disease that causes so much suffering and disability,” says Mr Sullivan.

For more information, contact scientist Annette C. Kuesel or communications officer Kristen Kelleher.

Related links
MDGH press release
Read the Lancet article
Research profile of moxidectin at TDR
TDRNews and events2018 News and press releases
© WHO 2021More about our sponsorsContact us
Special Programme for Research and Training in Tropical Diseases (TDR)

southernbubby

Thu, Sep 09 2021, 6:17 am

amother [ Tanzanite ] wrote:

It was not formulated to treat Covid but there are studies being done on it. It looks like underdeveloped countries where HCQ and ivermectin are more frequently used are also struggling to contain Covid so I am not sure if these medications are a factor or not. Maybe someone has some statistics but data may be hard to obtain from countries where much of the population is rural.

amother

Tanzanite

Thu, Sep 09 2021, 6:59 am

southernbubby wrote:

Actually there is one truth that we must seek.
And when it comes to falsehood it's the tool of Amalek to cast doubt and stir the pot so that truth is blurred.

amother

Seashell

Thu, Sep 09 2021, 6:59 am

I just saw this response from Dr. Zelenko.

The Zelenko Protocol was developed by me using hydroxychloroquine. I subsequently added the use of ivermectin when it was shown to work.

The devolved pagans have done everything possible to suppress access to these medication and have provided false fear mongering to the sheepish public.

The newest garbage on ivermectin is that a medication used billions of times is being blamed for reduction of sperm count in patients with river blindness from a Nigerian study from 2011.

Oh really, perhaps it is the parasitic disease that damage the scrotum of affected patients.

https://sti.bmj.com/content/80/1/12

Stop being stupid sheep.

Vladimir Zev Zelenko MD

P.S. Dear devolved pagans. You could have come with something more credible than a 10 year old study from Nigeria. I expect better.

Moonlight

Thu, Sep 09 2021, 7:07 am

Ivermectin is used on humans to treat scabies. All the time.

amother

Lawngreen

Thu, Sep 09 2021, 7:15 am

From Snopes.com:

The study in question was not published in a credible journal, nor was it hosted by an accredited, reputable institution. In the decade since the study’s supposed 2011 publication, there has been little — if any — related research to confirm its findings. Furthermore, a spokesperson for the U.S. Food and Drug Administration told Snopes that infertility in men is not a known side effect of ivermectin and, as such, is not included in U.S. labeling requirements.

amother

Lawngreen

Thu, Sep 09 2021, 7:16 am

southernbubby wrote:

Which countries?

amother

Strawberry

Thu, Sep 09 2021, 7:20 am

amother [ Lawngreen ] wrote:

Which countries?

India for one.
For a long time ppl said India had such mild covid bec HCQ and anti malaria drugs were som common.
But then covid exploded in India.

To me a study coming out of only Nigeria isn’t so reliable.

It’s been around for 40 yrs and In 2018, it was the 420th most commonly prescribed medication in the United States, with more than one hundred thousand prescriptions.
You would think if there was a risk it would be more widely studied and publicized.