Please recheck if u have antibodies...

amother

Powderblue

Sun, Jun 28 2020, 8:12 am

nchr wrote:

IgM you mean... not IgG which can be lifelong depending on the bacterium, parasite or virus.

IgM antibodies indicate an active infection. IgG antibodies develop later. They may or may not wear off.

amother

Tangerine

Sun, Jun 28 2020, 8:12 am

amother [ Coral ] wrote:

Antibodies dont last forever and protect for all mutations. For those who think it does. This isn't the mumps where if you got it once you are good for life.

That is why you can get the flu, type a & b in the same seaon or once in november and again in April. And that is why vaccines have booster schedules.

At best you can get maybe 6 months. 3 months is not uncommon. So if you had the virus purim time you are starting to become suseptible to getting it again now. Basic biology. This is in the corona class of viruses. It is not a bacteria.

Influenza viruses mutate much more than coronaviruses, so this isn't necessarily true.

SARS-CoV-2 and flu are biologically different
Both the new coronavirus and influenza have genetic material in the form of RNA. RNA viruses tend to accumulate a lot of mutations as they multiply – they typically don’t double-check copied genes to correct errors during replication. These mutations can occasionally lead to significant changes: The virus might change the species it infects or cell receptor it uses, or it could become more or less deadly, or spread more or less easily.

Uniquely, influenza’s genetic material is organized in segmented chunks. This idiosyncrasy means the virus can trade entire segments of RNA with other influenza viruses, enabling rapid evolution. Influenza also has a distinct seasonality, circulating much more during the winter months. As virus strains circulate, oscillating seasonally between the Northern and Southern Hemispheres’ wintertimes, they mutate rapidly. This capacity for quick adaptation is why you need to get a new flu vaccination annually to protect against new strains that have emerged in your area since last year.

SARS-CoV-2 makes many copies of itself once it successfully infects a human cell. dowell/Moment via Getty Images
Coronaviruses actually do proofread their copied RNA to fix inadvertent errors during replication, which decreases their relative mutation rate. From the originally sequenced SARS-CoV-2 in Wuhan, China in December 2019 to recently banked sequences from the U.S., there are fewer than 10 mutations in 30,000 potential locations in its genome, despite the virus having traveled around the world and through multiple generations of human hosts. Influenza makes 6.5 times more errors per replication cycle, independent of entire genome segment swaps.

The relative genetic stability of SARS-CoV-2 means that future peaks of disease are unlikely to be driven by natural changes in virulence due to mutation. Mutation is unlikely to contribute to predictable “waves” of COVID-19.

https://theconversation.com/co.....38895

nchr

Sun, Jun 28 2020, 8:15 am

amother [ Coral ] wrote:

Not really, MERS and SARS had protection of 3 to 5 years (with it waning beforethen). 3 months is probably not reasonable. It's likely more like 12-18 months but we don't know. We just need to compare it to other coronaviruses. Some viruses give lifelong immunity others give none at all (not even for a day) and others give some kind. We also do not know if there are healthy carriers (like with Herpes but not with measles). Since we do not know and we do not have any reliable way to test we need to be reasonable and follow reasonable guidelines like masks in public places (since this has been proven to prevent super spreading situations).

Last edited by nchr on Sun, Jun 28 2020, 8:16 am; edited 1 time in total

gold21

Sun, Jun 28 2020, 8:16 am

If covid antibodies really wear off after three months, we will be requiring a vaccine, which, much like the virus itself, imparts antibodies, every three months. Yikes.

gold21

Sun, Jun 28 2020, 8:20 am

The flu virus is a rapidly mutating virus. It's really difficult to vaccinate against successfully. It's not that the antibodies wear off but that the virus itself changes.

amother

Powderblue

Sun, Jun 28 2020, 8:25 am

The test for an active infection is more likely to give a false negative. Sticking a swab up someone's nose, it's possible you didn't go far enough and there's not enough mucous to catch the virus and can have a false negative.

The antibody test, from specific (widely used) labs like Quest, are 96% accurate if they do detect antibodies. There's a slight chance that you had a different coronavirus and that is what the test is picking up on. But again, very slight as they are 96% accurate in detecting antibodies.

As others noted, lack of antibodies does not mean lack of immunity, it is just not known.

Also, no location that had a large outbreak, has yet had a second outbreak in that location. Thus, the medical community is coming toward a consensus that there is probably herd immunity within a specific locale, and that it probably lasts at least 6 months, since that's how long it's been since the initial outbreak in Wuhan in January.

amother

Coral

Sun, Jun 28 2020, 8:38 am

I was pointing out the maximum time you can rely safely on antibodies. If it lasts longer only the future will tell. But at what point after antibidies does it make sense to protect the suseptible again?

amother

Jetblack

Sun, Jun 28 2020, 8:44 am

People are using the claim "tests are not reliable" to fit their own agenda.

The covid tests are not reliable.
The antibody tests are not reliable.
So nobody should assume anything.

If that's the case, then the OPs supposed situation is no proof either. Maybe those people didn't have the first time, maybe they didn't have antibodies, maybe they don't have it now.

Mama Bear

Sun, Jun 28 2020, 9:02 am

I tested myself for antibodies simply bc I was curious to know if the illness I had purim time was Covid. I never thought it keeps me immune forever.
In my experience you can have on-and-off flare-ups of Covid. It's a virus. I often have 24-48 hours of feeling ill, headache, achey joints, lump in my throat, etc. -- and I'm fine a day or two later. It might be a recurrence of covid, it might stam be a stress reaction in my body. It happens usually when I'm really stressed and overwhelmed by life.

nchr

Sun, Jun 28 2020, 9:05 am

amother [ Powderblue ] wrote:

IgM antibodies indicate an active infection. IgG antibodies develop later. They may or may not wear off.

Yes I know that..... I assume clowny was confusing her info with IgM..

FranticFrummie

Sun, Jun 28 2020, 10:43 am

Interesting article: https://www.healthline.com/hea.....-line There were other related articles, but this one is the first one I could find that wasn't behind a paywall.

Basically, a lot of scientists are saying that it's not a new secondary infection, but rather a reactivation of the original infection.

Other scientists are saying that it's highly unlikely, because there has never been a Coronavirus that has a resting and reactivating stage, like herpes, shingles, or HIV.

All scientists agree that they don't have enough data, and can't say anything for certain.

Just wear your dang mask already! 😷

amother

Puce

Sun, Jun 28 2020, 2:00 pm

amother [ Gray ] wrote:

What does any of this have to do with the subject of antibodies “wearing off”?

Of course it has to do with antibodies wearing off. Many (if not most) people are more afraid to spread the virus than they are to catch it. Usually it's the older and more vulnerable population who is actually scared of the virus itself, and the younger, healthier people who would rather get on with life and risk catching it, but don't want to spread it to others.

With this information that the second time the virus is caught it is not contagious, that fear is gone. That means that anyone who is not afraid FOR THEMSELVES and has already caught the virus and recovered, can safely go out without fear. Even if their antibodies have worn off.

amother

Puce

Sun, Jun 28 2020, 2:01 pm

PinkFridge wrote:

You mean even if they can catch it a second time they can't spread it a second time?

Yes, exactly.

Miri1

Sun, Jun 28 2020, 2:24 pm

amother [ Puce ] wrote:

Yes, exactly.

Any notions to that tune are really in the theoretical stage. No-one can assume that at this point, there simply isn't the data to determine that.
You need time to tell if a second infection is or is not infectious.

Also, I believe the population in Wuhan is much more compliant with protective measures such as mask wearing, so we don't really know whether it is that or herd immunity that has protected them. (We also don't really know numbers - it is China after all)

I do also wonder if someone who was sick Purim time was actually tested? Or just assumed they were sick with Covid. Tests weren't readily available then, so they would have had to be pretty sick to have been tested.

amother

Orange

Mon, Jun 29 2020, 6:46 am

Miri1 wrote:

Yup. Didn't get tested though no question. Besides losing taste and smell.
But we did participate in a plasma drive and have antibodies.

youngishbear

Mon, Jun 29 2020, 6:56 am

gold21 wrote:

If covid antibodies really wear off after three months, we will be requiring a vaccine, which, much like the virus itself, imparts antibodies, every three months. Yikes.

Unless...

We can manage to quickly immunize EVERYBODY (or at least, enough people to get to the necessary threshold, whatever that might be) so that the virus has nowhere to go and dies out before anyone loses immunity.

The worst-case scenario for infectious disease specialists is the one where the virus keeps circulating from place to place, coming back for a second round when immunity from the first one has faded, and on and on.

Ora in town

Mon, Jun 29 2020, 8:27 am

I just heard that the Ig G antibodies vanish quite rapidly (do not appear in the test after a few weeks or months), but this does not mean that the immunity is not given any more...

amother

Forestgreen

Tue, Jun 30 2020, 9:40 am

If it is possible to get reinfected why are there no studies showing that?

Goldie613

Tue, Jun 30 2020, 10:46 am

imokay wrote:

Disappearing antibodies does not mean no immunity. Scientists are still trying to understand all the data and what all this signifies.
Please stop spreading fear and gossip and rumors. If you have a reputable scientific article to link to then that is welcome information.

Here you go :-(

I agree we have more to learn, but until we know anything for sure, I figure better safe than sorry

https://abcnews.go.com/Health/.....06787

imokay

Tue, Jun 30 2020, 10:51 am

Goldie613 wrote:

Here you go :-(

I agree we have more to learn, but until we know anything for sure, I figure better safe than sorry

https://abcnews.go.com/Health/.....06787

All that article says is that antibodies fade but scientists don't know what that means.